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An Asymmetric Formal Synthesis of Fasicularin.

✍ Scribed by Michael D. B. Fenster; Gregory R. Dake

Publisher
John Wiley and Sons
Year
2006
Weight
11 KB
Volume
37
Category
Article
ISSN
0931-7597

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An Asymmetric Formal Synthesis of Fasicu
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An efficient asymmetric synthesis of enantiomerically pure (+)\_pilosinine 4 has been achieved in 6 steps from a known chiral bromoacyloxaxolidinone. The imidaxole alkaloid (+)-pilocarpine 1 and analogs have been the subject of considerable study of late due to their therapeutic potential as muscari