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Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice

โœ Scribed by Po C. Chan; Joel Mahler; Shyamal Peddada; Liat Lomnitski; Abraham Nyska


Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
357 KB
Volume
77
Category
Article
ISSN
0340-5761

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr