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Following the Development of a CD4 T Cell Response In Vivo: From Activation to Memory Formation

✍ Scribed by Sylvie Garcia; James DiSanto; Brigitta Stockinger

Book ID: 117722520
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 122 KB
Volume: 11
Category: Article
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(00)80091-6

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## Abstract Naturally occurring CD4^+^ regulatory T cells can be identified on the basis of expression of CD25 and suppression of T cell responses __in vitro__ after TCR triggering. Here, we demonstrate that a CD134^+^ subset of CD4^+^CD25^+^ T cells in naive rats suppresses antigen‐specific T cell