✦ LIBER ✦

Fluoride-catalyzed Michael addition of nitrotoluenes to activated α, β-unsaturated esters

✍ Scribed by Wen-Sen Li; John Thottathil; Michael Murphy

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 217 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)73443-5

No coin nor oath required. For personal study only.

✦ Synopsis

We have found that in the presence of fluoride ion, nitrotoluenes of type 1 undergo Michael addition to activated a, p-unsaturated esters of type 2 in good to excellent yield (Scheme 1). The generality and limitation of this reaction and its application to the chiral synthesis of benzazepine 4 are described.

📜 SIMILAR VOLUMES

Rhodium-catalyzed michael additions of a

Rhodium-catalyzed michael additions of activated nitriles to α,β - unsaturated esters

✍ Stefano Paganelli; Alberto Sehionato; Carlo Botteghi 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 238 KB

Highly Efficient InBr3 Catalyzed Michael

Highly Efficient InBr3 Catalyzed Michael Addition of Indoles to α,β-Unsaturated Esters

✍ Ping Liu; Wei Chen; Kai Ren; Prof. Dr. Lei Wang 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB 👁 1 views

NHC-Catalyzed Michael Addition to α,β-Un

NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation

✍ Suman De Sarkar; Prof. Dr. Armido Studer 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 1 views

A stereoselective michael addition of α-

A stereoselective michael addition of α-lithiated phosphonates to α,β-unsaturated esters

✍ Masahiko Yamaguchi; Yukiharu Tsukamoto; Akio Hayashi; Toru Minami 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 123 KB

a-Lithiated phosphonates added to a&unsaturated t-butyl esters in 1,Gmanner giving anti-3,4-disubstituted-4-phosphorylbutanoates in high yields. /~~%~ylam%omethyl)phosphonates were prepared from dialkyl phosphite, dibenzylamine, and formaldehyde: See; R. Tyka, Tetrahedron Lett., 1970, 677.

ChemInform Abstract: Highly Efficient In

ChemInform Abstract: Highly Efficient InBr3 Catalyzed Michael Addition of Indoles to α,β-Unsaturated Esters.

✍ Ping Liu; Wei Chen; Kai Ren; Lei Wang 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 36 KB 👁 2 views

ChemInform Abstract: NHC-Catalyzed Micha

ChemInform Abstract: NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation.

✍ Suman De Sarkar; Armido Studer 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 51 KB

## Abstract Enals react with various 1,3‐dicarbonyl compounds as redox‐activated Michael acceptors in the presence of TAZ as NHC precursor and a bisphenol derived quinone TBQ as the organic oxidant to produce dihydropyranones.