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A stereoselective michael addition of α-lithiated phosphonates to α,β-unsaturated esters

✍ Scribed by Masahiko Yamaguchi; Yukiharu Tsukamoto; Akio Hayashi; Toru Minami

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
123 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis

a-Lithiated phosphonates added to a&unsaturated t-butyl esters in 1,Gmanner giving anti-3,4-disubstituted-4-phosphorylbutanoates in high yields.

/~~%~ylam%omethyl)phosphonates were prepared from dialkyl phosphite, dibenzylamine, and formaldehyde: See; R. Tyka, Tetrahedron Lett., 1970, 677.

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