𝔖 Bobbio Scriptorium
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Fluorescein-labeled stable neurotensin derivatives

✍ Scribed by Veronique Maes; Christina Hultsch; Suzann Kohl; Ralf Bergmann; Thomas Hanke; Dirk Tourwé

Book ID
105360579
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
141 KB
Volume
12
Category
Article
ISSN
1075-2617

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✦ Synopsis

Neurotensin(8-13) analogs containing a glycine or 5-aminovaleroyl spacer were labeled with fluorescein through formation of an N-terminal thiourea function. The receptor binding was measured in HT-29 cell cultures and showed a substantial decrease in affinity, especially for the metabolically stabilized [MeArg(9), Tle(11)] analog. Using fluorescence microscopy, the internalization of the fluorescent neurotensin analogs into HT-29 cells was observed.

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Preparation of some mercuri-derivatives
Preparation of some mercuri-derivatives of fluorescein labelled with isotopes 197Hg and 203Hg. III. Recoil-labelling of derivatives
✍ L. Kronrád; J. Ratuský; P. Málek; B. Vavrejn; J. Kolc 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 300 KB

## Abstract The possibility of preparation of mercuriderivatives of fluorescein labelled with ^197^ Hg by irradiation of the respective compounds in a nuclear reactor has been studied. For all investigated compounds, specific activity high enough could be obtained without any significant radiation