Flexible synthetic route to 6-deoxy and 11-deoxyanthracyclinones
โ Scribed by F. Angelucci; G. Barchielli; G.A. Brussani; M. Gigli; B. Gioia; R. Hermann; A. Suarato; E. Vanotti; S. Penco
- Book ID
- 104233364
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 245 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
+)-7-Deoxy-6-epicastanospermine 1, (-)-7,8-dideoxy-6-epicastanospermine 2 and (-)-Nacetylslaframine 4 have been synthesized via the stereoselective intramolecular iodocyclization of trichloroacetimidates generated from cis-olefinic allylic alcohols 7 and 15, respectively.
In our investigation of the substrate specificity of 2-deoxy-n-ribose kinase isolated from Salmonella typhimurium, we required 2-deoxy-nribose (2-deoxy-L-erythro-pentose) (1) and 2-deoxy-D-xylose (2-deoxyn-threo-pentose) (2). Of the known methods for the preparation of these sugars (3, 4), the gly