Flavivirus RNA cap methyltransferase: structure, function, and inhibition
โ Scribed by Lihui Liu; Hongping Dong; Hui Chen; Jing Zhang; Hua Ling; Zhong Li; Pei-Yong Shi; Hongmin Li
- Book ID
- 107382807
- Publisher
- SP Higher Education Press
- Year
- 2010
- Tongue
- English
- Weight
- 723 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1674-7984
No coin nor oath required. For personal study only.
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Several potential inhibitors of mRNA guanine 7-methyltransferase, which were designed from mechanism-based considerations, were evaluated against the vaccinia virus capping enzyme complex. Of the compounds tested, 5'-deoxy-5'[6-(2-aminopyrrolo[2,3-d]-pyrimidine-4-one) methylthio]adenosine (9) had go