✦ LIBER ✦

FK506 (Tacrolimus) decreases the cytotoxicity of cyclosporin A in rat hepatocytes in primary culture: implication of CYP3A induction

✍ Scribed by Sophie Ellouk-Achard; Chantal Martin; Huynh Thien Duc; Hélène Dutertre-Catella; Marc Thevenin; Jean-Michel Warnet; Jean Roger Claude

Publisher: Springer-Verlag
Year: 1998
Tongue: English
Weight: 707 KB
Volume: 72
Category: Article
ISSN: 0340-5761
DOI: 10.1007/s002040050499

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Implication of CYP 3A in the toxicity of

Implication of CYP 3A in the toxicity of cyclosporin G (CsG), cyclosporin A (CsA) and FK506 on rat hepatocytes in primary culture

✍ Sophie Ellouk-Achard; Chantal Martin; Chuong Pham-Huy; Huynh Thien Duc; Marc The 📂 Article 📅 1997 🏛 Springer-Verlag 🌐 English ⚖ 339 KB

Increased activity of CYP3A enzyme in pr

Increased activity of CYP3A enzyme in primary cultures of rat hepatocytes treated with docetaxel: comparative evaluation with paclitaxel

✍ Srikanth C. Nallani; Mary Genter; Pankaj B. Desai 📂 Article 📅 2001 🏛 Springer 🌐 English ⚖ 181 KB

Effect of cell density and epidermal gro

Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture

✍ J Greuet; L Pichard; J C Ourlin; C Bonfils; J Domergue; P Le Treut; P Maurel 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 411 KB 👁 2 views

The influence of cell density and epidermal growth factor (EGF) on the expression and inducibility of cytochrome P450 (CYP) genes of the CYP3A and CYP1A families in adult human hepatocytes in primary culture has been evaluated. Only when cultured at subconfluence and in the presence of EGF did hepat

A comparison of the effect of inducers o

A comparison of the effect of inducers on the expression of glutathione-S-transferases in the liver of the intact rat and in hepatocytes in primary culture

✍ S Langouet; F Morel; D J Meyer; O Fardel; L Corcos; B Ketterer; A Guillouzo 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 702 KB

the prevention of AFB 1 -associated liver cancer in huphy. mans, provided they are nontoxic and increase levels From 1 INSERM U49, Unite ´de Recherches He ´patologiques, Ho ˆpital Pontof those GSTs that are effective enzymes for the carcichaillou, Rennes, France; and 2 Cancer Research Campaign, Mol