The first total synthesis of (ร)-bitungolide E is described. The key steps include a Myers' alkylation, modified Evans' syn aldol-reaction, using Crimmins protocol, Sharpless asymmetric epoxidation and ringclosing metathesis reaction.
First Total Synthesis of the Marine Illudalane Sesquiterpenoid Alcyopterosin E.
โ Scribed by Bernhard Witulski; Axel Zimmermann; Nicholas D. Gowans
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 146 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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