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First Synthesis of a Fully Phosphorylated GPI Membrane Anchor: Rat Brain Thy-1

✍ Scribed by Campbell, A. Stewart; Fraser-Reid, B.


Book ID
111973056
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
225 KB
Volume
117
Category
Article
ISSN
0002-7863

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Disintegration of the target molecule 1 into building blocks A-E was performed. For D, an efficient synthesis of mannose derivative 5, representing mannose residue c in the target molecule, could be performed; 5 permits the required regioselective access to C-I, 2-0, 4-0, and 6-0. Reaction of 5 with