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A ready, convergent synthesis of the heptasaccharide GPI membrane anchor of rat brain Thy-1 glycoprotein

✍ Scribed by Udodong, Uko E.; Madsen, Robert; Roberts, Carmichael; Fraser-Reid, Bert

Book ID
120323815
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
220 KB
Volume
115
Category
Article
ISSN
0002-7863

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Disintegration of the target molecule 1 into building blocks A-E was performed. For D, an efficient synthesis of mannose derivative 5, representing mannose residue c in the target molecule, could be performed; 5 permits the required regioselective access to C-I, 2-0, 4-0, and 6-0. Reaction of 5 with