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First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

✍ Scribed by Mercey, Guillaume; Verdelet, Tristan; Saint-André, Géraldine; Gillon, Emilie; Wagner, Alain; Baati, Rachid; Jean, Ludovic; Nachon, Florian; Renard, Pierre-Yves

Book ID
111965121
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
654 KB
Volume
47
Category
Article
ISSN
1359-7345

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ChemInform Abstract: First Efficient Unc
ChemInform Abstract: First Efficient Uncharged Reactivators for the Dephosphylation of Poisoned Human Acetylcholinesterase.
✍ Guillaume Mercey; Tristan Verdelet; Geraldine Saint-Andre; Emilie Gillon; Alain 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 22 KB

## Abstract The title compounds (I) are extremely promising uncharged reactivators for poisoned human AChE with a superior or similar in vitro ability to reactivate the enzyme as that of HI‐6, obidoxime, TMB‐4 and HL‐7.