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First chiral [2.2]paracyclophane-derived phosphite ligands: synthesis and application in asymmetric reactions

โœ Scribed by S. E. Lyubimov; R. P. Zhuravskii; V. I. Rozenberg; A. S. Safronov; P. V. Petrovskii; V. A. Davankov


Book ID
106520758
Publisher
Springer
Year
2008
Tongue
English
Weight
251 KB
Volume
57
Category
Article
ISSN
1573-9171

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Novel chiral tridentate Schiff base liga
โœ Tatyana I. Danilova; Valeria I. Rozenberg; Elena V. Sergeeva; Zoya A. Starikova; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 268 KB

The first example of the efficient application of chiral tridentate N,O-[2.2]paracyclophane ligands of the imino type for enantioselective diethylzinc addition to aliphatic and aromatic aldehydes is presented. The enantiomeric excess of the resulted secondary alcohols is up to 93% e.e.