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[2.2]Paracyclophane-Derived Chiral P,N-Ligands: Design, Synthesis, and Application in Palladium-Catalyzed Asymmetric Allylic Alkylation

โœ Scribed by Jiang, Biao; Lei, Yang; Zhao, Xiao-Long


Book ID
125897381
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
211 KB
Volume
73
Category
Article
ISSN
0022-3263

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Novel planar chiral P,N-[2.2]paracycloph
โœ Xun-Wei Wu; Ke Yuan; Wei Sun; Ming-Jie Zhang; Xue-Long Hou ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 251 KB

A series of planar chiral P,N-[2.2]paracyclophane ligands were synthesized and applied in enantioselective palladiumcatalyzed allylic alkylation, in which the central chirality of [2.2]paracyclophane is the dominant stereocontrol element. The effect of the substituents attached to the phosphorus ato