Fine specificity of the anti–citrullinated protein antibody response is influenced by the shared epitope alleles
✍ Scribed by K. N. Verpoort; K. Cheung; A. Ioan-Facsinay; A. H. M. van der Helm-van Mil; J. K. de Vries-Bouwstra; C. F. Allaart; J. W. Drijfhout; R. R. P. de Vries; F. C. Breedveld; T. W. J. Huizinga; G. J. M. Pruijn; R. E. M. Toes
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 57 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic citrullinated peptide (anti‐CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). ## Methods We studied 1,723 Caucasian RA patients enrolled in the
## Abstract ## Objective Anti–citrullinated protein antibodies (ACPAs) display high association with rheumatoid arthritis (RA) and are implicated in its pathogenesis. The presence of ACPAs is known to precede the onset of RA. In order to identify the features that could confer its pathogenicity, w