𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fibroblast culture in Werner's syndrome

✍ Scribed by Nienhaus, Anneke J. ;Jong, B. ;Kate, L. P. ;Oswald, F. H.


Publisher
Springer-Verlag
Year
1971
Weight
165 KB
Volume
13
Category
Article
ISSN
0018-7348

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Induction of DNA polymerase Ξ± in senesce
✍ W. R. Pendergrass; A. C. Saulewicz; D. Salk; T. Norwood πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 639 KB

DNA polymerase alpha activity was determined following serum stimulation of early and late passages of human diploid fibroblast-like (HDFL) cultures derived from apparently normal donors (two strains) and from a patient with Werner's syndrome (one strain). Induction of this enzyme was observed in bo

A retarded rate of DNA replication and n
✍ Yoshisada Fujiwara; Toshiaki Higashikawa; Mariko Tatsumi πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 685 KB

## Abstract We investigated the cloning efficiency, DNA repair, and the rate of DNA replication in the skin fibroblasts from patients with Werner's syndrome (WS) of an autosomal recessive premature aging disease. Five WS strains exhibited normal levels of sensitivity toward X‐ray and UV killings an

Werner's syndrome – chromosome analyses
✍ K. MORITA; C. NISHIGORI; M.S. SASAKI; N. MATSUYOSHI; K. OHTA; H. OKAMOTO; K. IKA πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 986 KB

Two cases of Werner's syndrome are reported. Fibroblasts derived from both patients revealed reduced population doubling numbers. Chromosomal analyses for fibroblasts from both patients and lymphocytes from one patient revealed that chromosomal aberrations occur frequently and randomly. Although som

Bloom's syndrome: DNA replication in cul
✍ Roger Hand; James German πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 639 KB

Analysis of DNA fiber autoradiograms from Bloom's syndrome skin fibroblasts and blood lymphocytes shows a retarded rate of replication fork movement compared to normal adult controls. Other measurements from the autoradiograms--replication unit length, incidence of bidirectional replication, and deg

Life span elongation of Werner's syndrom
✍ T. Ohno; N. Yamaguchi πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 179 KB

Co-culturing with origin-defective SV40 DNAinjected transformants, we succeeded in activating the limited growth potential of late-phase-II fibroblasts from patients with Werner's syndrome (WS cells). Residual life spans of three WS cell lines increased 2.3-5.6 fold. Co-culture with normal IMR-90 ce