✦ LIBER ✦
Life span elongation of Werner's syndrome fibroblasts by co-culture with origin-defective SV-40 DNA transformed cells
✍ Scribed by T. Ohno; N. Yamaguchi
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 179 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
Co-culturing with origin-defective SV40 DNAinjected transformants, we succeeded in activating the limited growth potential of late-phase-II fibroblasts from patients with Werner's syndrome (WS cells). Residual life spans of three WS cell lines increased 2.3-5.6 fold. Co-culture with normal IMR-90 cells showed variable effects on different WS cell lines.