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Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype

โœ Scribed by Ngo, Duyen; Bae, Harold; Steinberg, Martin H.; Sebastiani, Paola; Solovieff, Nadia; Baldwin, Clinton T.; Melista, Efthymia; Safaya, Surinder; Farrer, Lindsay A.; Al-Suliman, Ahmed M.; Albuali, Waleed H.; Al Bagshi, Muneer H.; Naserullah, Zaki; Akinsheye, Idowu; Gallagher, Patrick; Luo, Hong-yuan; Chui, David H.K.; Farrell, John J.; Al-Ali, Amein K.; Alsultan, Abdulrahman


Book ID
120657692
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
235 KB
Volume
51
Category
Article
ISSN
1079-9796

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Two population groups from Western India with a high prevalence of the โค S gene, one tribal (Valsad) and the other nontribal (Nagpur), were studied. The โค S gene frequency in both populations was similar (0.22 vs. 0.23), but not the clinical expression of sickle-cell anemia (SS): the sickle homozygo