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Genetic studies of fetal hemoglobin in the Arab-Indian haplotype sickle cell-β 0 thalassemia

✍ Scribed by Alsultan, Abdulrahman; Ngo, Duyen; Bae, Harold; Sebastiani, Paola; Baldwin, Clinton T.; Melista, Efthymia; Suliman, Ahmed M.; Albuali, Waleed H.; Nasserullah, Zaki; Luo, Hong-yuan; Chui, David H.K.; Steinberg, Martin H.; Al-Ali, Amein K.

Book ID: 120645530
Publisher: John Wiley and Sons
Year: 2013
Tongue: English
Weight: 333 KB
Volume: 88
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.23434

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Two population groups from Western India with a high prevalence of the ␤ S gene, one tribal (Valsad) and the other nontribal (Nagpur), were studied. The ␤ S gene frequency in both populations was similar (0.22 vs. 0.23), but not the clinical expression of sickle-cell anemia (SS): the sickle homozygo