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Fertility and apparent genetic anticipation in Lynch syndrome

✍ Scribed by Stupart, Douglas; Win, Aung Ko; Jenkins, Mark; Winship, Ingrid M.; Goldberg, Paul; Ramesar, Rajkumar

Book ID
125360134
Publisher
Springer Netherlands
Year
2014
Tongue
English
Weight
318 KB
Volume
13
Category
Article
ISSN
1389-9600

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## Abstract Anticipation, manifested through decreasing age of onset or increased severity in successive generations, has been noted in several genetic diseases. Statistical methods for genetic anticipation range from a simple use of the paired __t__‐test for age of onset restricted to affected par