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No evidence of genetic anticipation in a large family with Lynch syndrome

✍ Scribed by D. Stupart, P. Goldberg, U. Algar, A. Vorster, R. Ramesar

Book ID
120961669
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
271 KB
Volume
13
Category
Article
ISSN
1389-9600

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## Abstract Anticipation, manifested through decreasing age of onset or increased severity in successive generations, has been noted in several genetic diseases. Statistical methods for genetic anticipation range from a simple use of the paired __t__‐test for age of onset restricted to affected par