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Fenitrothion-induced changes in lipids of rats

โœ Scribed by Shalini Roy; Sharmila Roy; C. B. Sharma

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
373 KB
Volume
18
Category
Article
ISSN
0269-3879

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โœฆ Synopsis

Abstract

The doseโ€dependent lipid accumulation caused by fenitrothion administration is associated with alteration of the ratio of various components of phospholipids and neutral lipids in various organs of rats up to 48 h. The concentration of triacylglycerol, phosphatidyl choline, phosphatidyl ethanolamine and phosphatidyl glycerol increased in liver, kidney and brain in treated rats whereas phosphatidyl serine was greatly reduced. Highโ€performance liquid chromatography and gasโ€“liquid chromatography were used for quantiative analysis of phospholipids and triacylglycerol. The changes in relative composition of various lipids by fenitrothion administration may lead to malfunctioning and alteration of biological properties. Copyright ยฉ 2004 John Wiley & Sons, Ltd.

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