Neurofibromatosis type 1 (NF1) is characterized by the formation of neurofibromas, benign tumors of the peripheral nerve consisting essentially of Schwann cells, which can sometimes turn malignant to form neurofibrosarcomas. The mechanism of progression toward a malignant phenotype remains largely u
Febrile Response Induced by Platelet-Derived Growth Factor (PDGF) in Rats
✍ Scribed by IRENE R. PELÁ; MÁRCIA E. S. FERREIRA; MIRIAM C. C. MELO; CARLOS A. A. SILVA; C. FERNANDO VALENZUELA
- Book ID
- 111393695
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 319 KB
- Volume
- 856
- Category
- Article
- ISSN
- 0890-6564
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## Abstract Since meniscal healing is region‐specific, we studied the regional (peripheral compared with central) response of meniscal explants to human, recombinant platelet‐derived growth factor‐AB. Mensical explants from the hindlimbs of both knees of mature sheep were sectioned and were culture
Steady-state levels of rat central nervous system (CNS) platelet-derived growth factor (PDGF) A-and B-chain mRNAs were measured by a polymerase chain reaction method employing a synthetic gene internal standard, and the rates of transcription of PDGF A-and B-chain genes in CNS were estimated by a nu