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๐ SIMILAR VOLUMES
VOLUME 110 โข NUMBER 4 ## FEATURES Cytology is the fi eld of medicine in which various morphologic "criteria of malignancy" are applied to individual cells and small tissue fragments to diagnose cancer. Surprisingly little is known about the molecular basis of many of these defi ning structural fe
VOLUME 110 โข NUMBER 5 ## FEATURES A hallmark of acute myeloid leukemias (AMLs) is the presence of recurrent chromosomal rearrangements. Two common rearrangments, inv(16) and t(8;21), generate fusion genes with members of the Core Binding Factor (CBF) family of transcription factors, CBFB and RUNX
Stem and progenitor cells from a variety of sources may provide effective treatments for regenerative medicine. In their prospect, Shimada and Spees review current issues and hurdles facing cell-based treatments for diseased and injured neurological tissues. Several questions are addressed: Are stem
Piwi proteins are known to be critical for stem cell maintenance during development, especially in the germline, where they associate exclusively with a class of small RNAs called piwi-interacting RNAs (piRNA). Together, Piwi and piRNAs maintain genomic integrity by silencing transposon repeats thro