Feasibility of the thermodynamically controlled synthesis of amoxicillin
β Scribed by M.B. Diender; A.J.J. Straathof; L.A.M. van der Wielen; C. Ras; J.J. Heijnen
- Book ID
- 114396343
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 96 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1381-1177
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The 70 eV mass spectra of (3u) and (36) contain as fragments of highest mass number [M-C6Ho -CO] +. The molecular ions can be observed in the F-D spectrum (Varian 31 1 A). We thank Dr. K. K. Mayer and F. Fischer for recording the spectra.
A conductimetric method was developed for the monitoring of thermodynamically-controlled enzyme peptide synthesis. It was applied to the synthesis of Na-benzyloxycarbonylalanylphenylalaninamide, in the presence of Pseudomonas aeruginosa elastase. A linear continuous decrease of conductance could be