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Thermodynamically Controlled Stereoselective Synthesis of Geissoschizine

โœ Scribed by Dipl.-Chem. Werner Benson; Prof. Dr. Ekkehard Winterfeldt


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
223 KB
Volume
18
Category
Article
ISSN
0044-8249

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โœฆ Synopsis


The 70 eV mass spectra of (3u) and (36) contain as fragments of highest mass number [M-C6Ho -CO] +. The molecular ions can be observed in the F-D spectrum (Varian 31 1 A). We thank Dr. K. K. Mayer and F. Fischer for recording the spectra.


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A Concise, Stereoselective Synthesis of (ยฑ)-Geissoschizine. -The stereoselective synthesis of (ยฑ)-geissoschizine (VIII) is based on the addition of the enolate derived from 1-acetylindole (I) to the pyridinium salt (II) and cyclization of the resultant 1,4-dihydropyridine. -(BENNASAR, M.-L.;