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FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects

✍ Scribed by Giudici, D.; Briatico, G.; Cominato, C.; Zaccheo, T.; Iehlè, C.; Nesi, M.; Panzeri, A.; di Salle, E.

Book ID
121885188
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
684 KB
Volume
58
Category
Article
ISSN
0960-0760

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FRM146687, a novel steroid 5α-reductase
FRM146687, a novel steroid 5α-reductase inhibitor: In vitro and in vivo effects on prostates
✍ Nakayama, Osamu; Hirosumi, Jiro; Chida, Noboru; Takahashi, Satoru; Sawada, Kozo; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 524 KB

## BACKGROUND. Steroid 5␣-reductase is implicated in the pathogenesis of benign prostatic hyperplasia (BPH). We studied the in vitro and in vivo effects of FR146687, a new inhibitor of 5␣-reductase. METHODS. Two isozymes of rat and human 5␣-reductases were expressed in 293 cells. In vivo effects o