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Fc gamma receptor polymorphisms as predictive markers of Cetuximab efficacy in epidermal growth factor receptor downstream-mutated metastatic colorectal cancer

✍ Scribed by Javier Rodríguez; Ruth Zarate; Eva Bandres; Valentina Boni; Amaia Hernández; Jesus Javier Sola; Beatriz Honorato; Nerea Bitarte; Jesus García-Foncillas

Book ID
116430998
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
198 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Background: Researchers have recently reported an association between the epidermal growth factor receptor (egfr) pathway and platinum-chemotherapy sensitivity in cancer patients. the (ca)(n) repeat polymorphism in intron 1 of the egfr gene has been identified and found to alter egfr expression