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Gene Polymorphisms of Epidermal Growth Factor Receptor and its Downstream Effector, Interleukin-8, Predict Oxaliplatin Efficacy in Patients with Advanced Colorectal Cancer

✍ Scribed by Wu Zhang; Jan Stoehlmacher; David J. Park; Dongyun Yang; Erin Borchard; Ji Gil; Denice D. Tsao-Wei; Jim Yun; Michael Gordon; Oliver A. Press; Katrin Rhodes; Susan Groshen; Heinz-Josef Lenz

Book ID: 119934989
Publisher: CIG Media Group, LP.
Year: 2005
Tongue: English
Weight: 500 KB
Volume: 5
Category: Article
ISSN: 1533-0028
DOI: 10.3816/ccc.2005.n.025

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Gene Polymorphisms of Epidermal Growth Factor Receptor and its Downstream Effector, Interleukin-8, Predict Oxaliplatin Efficacy in Patients with Advanced Colorectal Cancer

✍ Wu Zhang; Jan Stoehlmacher; David J. Park; Dongyun Yang; Erin Borchard; Ji Gil; 📂 Article 📅 2005 🏛 CIG Media Group, LP. 🌐 English ⚖ 500 KB

## Background: Researchers have recently reported an association between the epidermal growth factor receptor (egfr) pathway and platinum-chemotherapy sensitivity in cancer patients. the (ca)(n) repeat polymorphism in intron 1 of the egfr gene has been identified and found to alter egfr expression