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Efficacy of Cetuximab After Treatment with Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor—Based Chemotherapy in Metastatic Colorectal Cancer

✍ Scribed by Jeffrey A. Meyerhardt; Denise Heseltine; Shuji Ogino; Jeffrey W. Clark; Peter C. Enzinger; David P. Ryan; Craig C. Earle; Andrew X. Zhu; Charles S. Fuchs


Book ID
119935044
Publisher
CIG Media Group, LP.
Year
2006
Tongue
English
Weight
147 KB
Volume
6
Category
Article
ISSN
1533-0028

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## Abstract ## BACKGROUND. Gefitinib, an orally active inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, combined with chemotherapy, has shown efficacy as second‐line treatment for advanced colorectal cancer (CRC). Gefitinib combined with FOLFOX6 (oxaliplatin plus folinic acid