Familial versus sporadic breast cancer
โ Scribed by David E. Anderson
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 740 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Women who have relatives known to have had breast cancer are at an increased risk of getting the disease compared with the general population. On the basis of an extensive collection of family trees of women with breast cancer, the magnitude of this increase in risk is computed. Previou
Human breast-cancer specimens from 100 patients were analyzed for microsatellite instability (referred to as replication error; RER) at I 2 genomic loci on 7 chromosomes, and results were correlated with clinicopathologic characteristics. In 42 of I00 breast-cancer patients, we investigated whether