This study was aimed at determining whether the familial clustering often observed in breast cancer is associated with genetic factors. We compared familial and sporadic breast cancer cases with respect to ABO blood group distribution and the risk of bilateral disease, using the data from the Icelan
Familial breast cancer in iceland
โ Scribed by Hrafn Tuljnius; Olafur Bjarnason; Gunnlaugur Geirsson; Gudmundur Johannesson; Helgi Sigvaldason; Gudrun Bjarnadotitr; Kristin Grimsdottir; Nicholas E. Day; Maria A. De Liceaga Gonzalez
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- French
- Weight
- 604 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
Abstract
Women who have relatives known to have had breast cancer are at an increased risk of getting the disease compared with the general population. On the basis of an extensive collection of family trees of women with breast cancer, the magnitude of this increase in risk is computed. Previously published results on other breast cancer risk factors are drawn upon and it has been possible to take account of some of these e.g., age, decade of birth, age at first childbirth and parity in the risk estimates. The relative risk with such adjustment is found to be 2.59 for mothers and 2.56 for sisters.
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All malignant tumours of the male breast diagnosed in Iceland during the 40-year period 1955-I994 were studied with regard to histological classification, tumour grading and flow cytometric analysis. Of 31 malignant tumours diagnosed, 29 were primary breast carcinomas. Male breast carcinoma constitu