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Familial Mutations in PMS2 Can Cause Autosomal Dominant Hereditary Nonpolyposis Colorectal Cancer

✍ Scribed by Daniel L. Worthley; Michael D. Walsh; Melissa Barker; Andrew Ruszkiewicz; Graeme Bennett; Kerry Phillips; Graeme Suthers

Book ID
119758545
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
316 KB
Volume
128
Category
Article
ISSN
0016-5085

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Mutation of the hMSH2 gene in two famili
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✍ Hae Mung Jeon; Patrick M. Lynch; Linda Howard; Jaffer Ajani; Bernard Levin; Mars πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 554 KB

Communicated by Sauiu L.C. Woo We examined 18 unrelated individuals who have colorectal cancer or cancers associated with the HNPCC syndrome and have a family history of cancer for mutations in exon 13 of the hMSH2 gene. Two of the 18 individuals had the same previously unreported single-base delet