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Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis

✍ Scribed by HF Vasen; JT Wijnen; FH Menko; JH Kleibeuker; BG Taal; G Griffioen; FM Nagengast; EH Meijers-Heijboer; L Bertario; L Varesco; ML Bisgaard; J Mohr; R Fodde; PM Khan


Book ID
119755328
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
94 KB
Volume
110
Category
Article
ISSN
0016-5085

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Mutation of the hMSH2 gene in two famili
✍ Hae Mung Jeon; Patrick M. Lynch; Linda Howard; Jaffer Ajani; Bernard Levin; Mars πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 554 KB

Communicated by Sauiu L.C. Woo We examined 18 unrelated individuals who have colorectal cancer or cancers associated with the HNPCC syndrome and have a family history of cancer for mutations in exon 13 of the hMSH2 gene. Two of the 18 individuals had the same previously unreported single-base delet