## Abstract Familial adenomatous polyposis (FAP) is a genetic disorder transmitted in an autosomal dominant pattern. Oneβhalf of members of an affected family will carry the gene, and all carriers will succumb to colon cancer or extracolonic manifestations if not detected and treated early. When th
Familial adenomatous polyposis. Surgical treatment: when and how
β Scribed by E. Contessini-Avesani; F. Botti; C. Negri; A. Carrara; B. Oreggia; F. Quadri; C. Bagni
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 110 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1123-6337
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Familial adenomatous polyposis (FAP) is a dominantly inherited familial cancer syndrome characterized by an increased predisposition to colorectal cancer and other benign and malignant extracolonic lesions. FAP has been linked to germline mutations of the adenomatous polyposis coli (APC) gene that e
A 43-year-old man presented with a lung nodule 19 years after undergoing a total colectomy for familial adenomatous polyposis (FAP). There had been no evidence of malignant transformation in the colectomy specimen, and current gastrointestinal investigation did not reveal evidence of tumor. Patholog