Familial adenomatous polyposis: A submicroscopic deletion at the APC locus in a family with mentally normal patients
✍ Scribed by Marion Mandl,Reiner Caspari,Anna Jauch,Thorsten Böker,Heidrun Raschke…
- Book ID
- 118291913
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 546 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0340-6717
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📜 SIMILAR VOLUMES
Endocrine neoplasms have been reported occasionally in patients with familial adenomatous polyposis (FAP). An adrenocorotical carcinoma was studied in a patient with a family history of FAP. Loss of heterozygosity (LOH) in the region close to the adenomatous polyposis coli (APC) gene was detected in
A family is presented with attenuated familial adenomatous polyposis of variable phenotype. The clinical features range from sparse right-sided polyposis and cancer in the proximal colon at the age of 34 to pan-colonic polyposis and cancer at the age of 68. Rectal sparing is common to all affected m