Factors influencing the inhibition of repair of irradiation-induced DNA damage by 2′-deoxycoformycin and deoxyadenosine
✍ Scribed by Asher Begleiter; Linda Verburg; Lyonel G. Israels; James B. Johnston
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 539 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0344-5704
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## Abstract DNA is exposed to endogenous and environmental factors that can form stable lesions. If not repaired, these lesions can lead to transcription/replication blocking or mutagenic bypass. Our previous work has focused on 8,5′‐cyclopurine 2′‐deoxyribonucleosides, a unique class of oxidativel
The comet assay was used to measure DNA dam-DNA damage was removed in 2 hr, even in the age and repair in nuclei released from 1 cm root presence of 3-aminobenzamide. Complete repair ends of Vicia faba after X-ray irradiation. Irradia-was inhibited by incubation on ice (30% of DNA tion induced a lin