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Factor V Q 506 mutation in children with thrombosis

✍ Scribed by Gurgey, Aytemiz; Mesci, Lutfiye; Renda, Yavuz; Olcay, Lale; Kocak, Nurten; Erdem, Gulsen

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 210 KB
Volume: 53
Category: Article
ISSN: 0361-8609
DOI: 10.1002/(sici)1096-8652(199609)53:1<37::aid-ajh8>3.0.co;2-6

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✦ Synopsis

The factor V Leiden mutation in 12-children with thrombosis and in 20 controls was investigated. Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found. Central nervous system thromboses were increased in children with the factor V mutation, associated with protein S deficiency.

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