Prevalence of the factor V-Leiden mutati
โ
Gregg, Jeff P.; Yamane, Akemi J.; Grody, Wayne W.
๐
Article
๐
1997
๐
John Wiley and Sons
๐
English
โ 8 KB
๐ 2 views
Resistance to activated protein C (APC) is the most common risk factor for venous thromboembolism, a major cause of morbidity and mortality with an incidence of about 1/1,000 per year. The Arg 506 to Gln mutation in exon 10 of the coagulation factor V gene (factor V-Leiden) has been found to be resp