Prevalence of the G1691A mutation in the factor V gene (factor V Leiden) and the G20210A prothrombin gene mutation in the Thai population
β Scribed by Pantep Angchaisuksiri; Sarinee Pingsuthiwong; Katcharin Aryuchai; Manisa Busabaratana; Thanyachai Sura; Vichai Atichartakarn; Piyamitr Sritara
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 28 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0361-8609
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The pathogenesis of venous thrombosis involves the interaction of genetic and environmental factors. In order to estimate the frequency of the factor V Leiden, the prothrombin G20210A, and the MTHFR C677T mutations in the Greek population, we analyzed 160 healthy Greek blood donors by PCR amplificat
Resistance to activated protein C (APC) is the most common risk factor for venous thromboembolism, a major cause of morbidity and mortality with an incidence of about 1/1,000 per year. The Arg 506 to Gln mutation in exon 10 of the coagulation factor V gene (factor V-Leiden) has been found to be resp