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Facile Uncatalyzed Mukaiyama Aldol Reactions: An ab Initio Study of the Effects of Substituents

✍ Scribed by Wong, Chiong Teck; Wong, Ming Wah


Book ID
126896079
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
204 KB
Volume
70
Category
Article
ISSN
0022-3263

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## Abstract The electrocyclization of 4‐substituted 3‐silyloxy‐2‐azadienes to β‐lactams was studied at the MP2/6‐31G\* level of theory and the effect of the substituents on the reactivity of the azadiene and on the stereochemistry of the cyclic products was evaluated. It was shown that the electroc