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Facile Synthesis of N-Alkyl-N‘-arylimidazolium Salts via Addition of Imidazoles to Arynes

✍ Scribed by Yoshida, Hiroto; Sugiura, Shinji; Kunai, Atsutaka


Book ID
111902375
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
45 KB
Volume
4
Category
Article
ISSN
1523-7060

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The synthesis of 1,2,4-trisubstituted imidazoles was demonstrated via the solid phase synthesis of N-alkyl-N-(bketo)amides using a carbazate linker. The approach enabled the assembly of a diverse number of N-alkyl-N-(b-keto)amide intermediates in good yield and purity. Subsequent cyclisation in solu