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Facile synthesis of isoindoline-1,3-diones by palladium-catalyzed carbonylative cyclization ofo-bromobenzoic acid and primary amines

✍ Scribed by Khedkar, Mayur V.; Bhanage, Bhalchandra M.


Book ID
120176523
Publisher
SP Higher Education Press
Year
2013
Tongue
English
Weight
150 KB
Volume
7
Category
Article
ISSN
2095-0179

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## Abstract 2‐Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3‐(alkylamino)isoindolin‐1‐ones in good yields.