Facile synthesis of deuterated estrogens
β Scribed by R.C. Murphy
- Book ID
- 118977941
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 373 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0039-128X
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## Abstract A general scheme for the synthesis of (__S__)β6βmethoxyβ2βpropanoic acid (naproxen) deuterated on the naphthyl ring, methoxy group, or both, is described. The resulting labeled naproxen derivatives are useful probes for examining atypical kinetics displayed by cytochrome P450 2C9. Copyr