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Facile synthesis of deuterated estrogens

✍ Scribed by R.C. Murphy


Book ID
118977941
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
373 KB
Volume
24
Category
Article
ISSN
0039-128X

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## Abstract A general scheme for the synthesis of (__S__)‐6‐methoxy‐2‐propanoic acid (naproxen) deuterated on the naphthyl ring, methoxy group, or both, is described. The resulting labeled naproxen derivatives are useful probes for examining atypical kinetics displayed by cytochrome P450 2C9. Copyr