Facile synthesis of 3-substituted quinazoline-2,4-dione and 2,3-di-substituted quinazolinone derivatives
β Scribed by Farouk, Mahmoud; Alrokayan, Salman A.; Imran, Ahamad; Abu-Salah, Khalid M.; Ghazzali, Mohamed; Al-Farhan, Khalid A.; El-Gohary, Salem; Adly, Mamdouh
- Book ID
- 118125413
- Publisher
- Versita
- Year
- 2013
- Tongue
- English
- Weight
- 219 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0366-6352
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π SIMILAR VOLUMES
A new synthesis of a series of 3-amino-1H-quinazoline-2,4-diones is described. The 1H-quinazoline-2,4dione 10 was made starting with fluorobenzoic acid in three high yielding steps. The key step of this synthesis involved the generation of the dianion of urea 7 and the subsequent intramolecular nucl
## Abstract magnified image A series of 2βsubstitutedβ4(3__H__)βquinazolinones **13β20** has been synthesized in good yields using the reaction of double lithiated 2βmethylquinazolinoneβ4 with a variety of aromatic aldehydes. They have been easily transformed in high yields into the corresponding
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