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Facile Synthesis of (2S,1′S,2′S)-2-(Carboxycyclopropyl)glycine, an Isotype-Selective Agonist of Metabotropic Glutamate Receptors

✍ Scribed by Dawei Ma; Zhaochun Ma


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
501 KB
Volume
38
Category
Article
ISSN
0040-4039

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Synthesis of (2S,1′ S,2′ S)-2-methyl-2-(
✍ Dawei Ma; Zhaochun Ma; Jiqing Jiang; Zhen Yang; Chongzhi Zheng 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 324 KB

The synthesis of two isotype-selective antagonists for metabotropic glutamate receptors, (2S, l'S,2'S)-2-methyl-2-(carboxycyclopropyl)glycine and (S)-2-amino-2methyl-4-phosphonobutyric acid from L-alanine is described. (~) 1997 Elsevier Science Ltd. All fights reserved.