Facile preparation of α-nitroketones from enol silyl ethers
✍ Scribed by Rajendra Rathore; Zhe Lin; Jay K. Kochi
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 274 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Treatment of enol silyl ethers with the mild nitrating agent tetranitromethane gives good yields of unitroketones at room temperature and below.
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Cyclic silyl enol ethers were successfully cleaved by EtOK to generate the corresponding enolates. Reactions with EtOK were faster and the corresponding enolates could be trapped by electrophiles and oxidants to give the kinetic products exclusively.
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