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Facile One-Pot Conversion of Aldehydes into Amides

โœ Scribed by Chill, Samuel T.; Mebane, Robert C.


Book ID
121267454
Publisher
Taylor and Francis Group
Year
2010
Tongue
English
Weight
187 KB
Volume
40
Category
Article
ISSN
0039-7911

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Facile One-Pot Conversion of Aldehydes i
โœ Chill, Samuel T.; Mebane, Robert C. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Taylor and Francis Group ๐ŸŒ English โš– 187 KB

A facile one-pot synthesis of amides from aldehydes has been developed. This tandem process involves the formation of a nitrile intermediate obtained from the reaction of an aldehyde with hydroxylamine hydrochloride in dimethylsulfoxide at 100 C and the subsequent treatment of the nitrile with basic