## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
Facile Asymmetric Synthesis of Aziridine Derivatives via the Diastereoselective Reaction of Chiral Imines with Dimethylsulfonium Methylide.
โ Scribed by Kimio Higashiyama; Masataka Matsumura; Ayako Shiogama; Takayasu Yamauchi; Sigeru Ohmiya
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 119 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
The Lewis acid mediated cyclization of y-oxygen substituted allylic stannane 1, having a chiral imine group at the terminus of the carbon chain, afforded trans ~amino cyclic ether 2 with very high to good diastereoselectivities in high chemical yields.
## Abstract For Abstract see ChemInform Abstract in Full Text.
Optically active a-arylglycine derivatives were synthesized by Brรธnsted acid (TFA)-promoted Friedel-Crafts reaction of various phenols with chiral cyclic glyoxylate imines (2a -c), followed by deprotection with Pd(OH) 2 /C under H 2 . The diastereoselectivities of the initially formed F-C reaction p
Asymmetric one-pot aziridination of imines with alkyl bromides via the imino Corey-Chaykovsky reaction mediated by chiral sulfide is described. The desired aziridines are obtained in good yields with up to 98% ee of the trans isomer.